Scientists have discovered that the enzyme TYK2 modifies tau proteins, leading to their accumulation in the brain--a key feature of Alzheimer's disease and related dementias. By reducing TYK2 activity in animal models, researchers found tau buildup was decreased, suggesting TYK2 inhibitors could be a potential therapeutic pathway.
Scientists have discovered that the enzyme TYK2 modifies tau proteins, leading to their accumulation in the brain--a key feature of Alzheimer's disease and related dementias. By reducing TYK2 activity in animal models, researchers found tau buildup was decreased, suggesting TYK2 inhibitors could be a potential therapeutic pathway.
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